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(2R,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-ol, also known as bromhexine, is a chemical compound with bronchodilator and mucolytic properties. It is a medication used to treat respiratory conditions such as bronchitis, asthma, and chronic obstructive pulmonary disease (COPD). (2R,3S)-3-(3-broMophenyl)-4-(4-chlorophenyl)butan-2-ol consists of a bromophenyl and chlorophenyl group attached to a butanol molecule, which gives it its therapeutic effects. Additionally, bromhexine has been shown to possess anti-inflammatory and antioxidant properties, making it a useful treatment for respiratory conditions.

941280-52-0

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941280-52-0 Usage

Uses

Used in Pharmaceutical Industry:
(2R,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-ol is used as a medication for treating respiratory conditions such as bronchitis, asthma, and chronic obstructive pulmonary disease (COPD). It functions as a bronchodilator, helping to relax and widen the airways, and as a mucolytic, thinning and loosening mucus in the airways to make it easier to cough up. The anti-inflammatory and antioxidant effects of bromhexine also contribute to its therapeutic benefits in respiratory conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 941280-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,1,2,8 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 941280-52:
(8*9)+(7*4)+(6*1)+(5*2)+(4*8)+(3*0)+(2*5)+(1*2)=160
160 % 10 = 0
So 941280-52-0 is a valid CAS Registry Number.

941280-52-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-ol

1.2 Other means of identification

Product number -
Other names (2R,3S)-2-(2,4-Difluorophenyl)-2,3-epoxy-1-butanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:941280-52-0 SDS

941280-52-0Downstream Products

941280-52-0Relevant academic research and scientific papers

Catalytic, enantioselective synthesis of taranabant, a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity

Chen, G-Yi,Frey, Lisa F.,Shultz, Scott,Wallace, Debra J.,Marcantonio, Karen,Payack, Joeseph F.,Vazquez, Enrique,Springfield, Shawn A.,Zhou, George,Liu, Ping,Kieczykowski, Gerard R.,Chen, Alex M.,Phenix, Brian D.,Singh, Utpal,Strine, Jeff,Izzo, Brianne,Krska, Shane W.

, p. 616 - 623 (2012/12/31)

Chiral amide 1 (MK-0364, taranabant) is a potent, selective, and orally bioavailable cannabinoid-1 receptor (CB-1R) inverse agonist indicated for the treatment of obesity. An asymmetric synthesis featuring a dynamic kinetic resolution via hydrogenation fo

Convenient total synthesis of taranabant (MK-0364), a novel cannabinoid-1 receptor inverse agonist as an anti-obesity agent

Kim, Min-ah,Kim, Jong Yup,Song, Kwang-Seop,Kim, Jeongmin,Lee, Jinhwa

, p. 12845 - 12852 (2008/03/27)

Being obese has various health problems that are related to type 2 diabetes mellitus, cardiovascular disease, hypertension, hyperlipidemia, and fibrinolytic abnormalities. Merck's taranabant (MK-0364), a CB1R inverse agonist, is currently in Phase 3 clini

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