94144-99-7

Upstream product

• 130691-00-8 (4E)-4-benzylidene-5-methyl-2-phenyl-3,4-dihydropyrazol-3(3H)-one 
• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 2981-10-4 1-(cyclohex-1-en-1-yl)piperidine 
• 135763-52-9 3-Methyl-8a-morpholin-4-yl-1,4-diphenyl-1,4,4a,5,6,7,8,8a-octahydro-chromeno[2,3-c]pyrazole 
• 135763-56-3 3-Methyl-1,4-diphenyl-8a-piperidin-1-yl-1,4,4a,5,6,7,8,8a-octahydro-chromeno[2,3-c]pyrazole 
• 39143-05-0 (Z)-4-benzylidene-3-methyl-1-phenyl-1H-pyrazolidinyl-5(4H)-ketone 
• 108-94-1 cyclohexanone 

Downstream Products

• 112920-99-7 5-amino-6-(3-methyl-5-oxo-1-phenyl-2-pyrazolin-4-yl)-6-phenylenanthylic acid 
• 112925-38-9 4-<(2'-ε-caprolactamyl)benzyl>-3-methyl-1-phenyl-2-pyrazolin-5-one 

Relevant academic research and scientific papers

Dihydropyrans from 1,4-cycloaddition of enamines to arylmethylenepyrazolones. Polar character of the thermal rearrangement of the resulting cycloadducts

The inverse electron demand hetero-Diels-Alder reaction of arylmethylenepyrazolones with enamines results in the selective formation of 3,4-dihydro-2H-pyran derivatives. These cycloadducts under thermodynamic conditions, are transformed via the zwitterion, which can be captured in the presence of tetracyanoethylene (TCE), as the more stable Michael-type adducts. The zwitterion could also be the intermediate for the cyclic adducts.

Synthesis of Some Pyrazolo-Anisylethylamine Alkaloids Amino Acids and Related Compounds

Schmidt reaction of the pyrazolo-β-(p-anisyl)-propionic acid 3 gave the pyrazolo-anisylethylamine 4.The related alkaloids 5 and 6 were obtained via double Mannich reaction of 4 with the bis-Mannich base of cyclopentanone and transamination with gramine re