94160-04-0

Upstream product

• 137-49-5 1-chloro-2-nitrobenzene-4-sulphonic acid phenylamide 
• 97-08-5 3-nitro-4-chlorosulfonyl chloride 
• 62-53-3 aniline 

Relevant academic research and scientific papers

Pyridine azo disperse dye containing sulfonic acid ester or sulfamine as well as synthesis method of pyridine azo disperse dye

The invention provides pyridine azo disperse dye containing sulfonic acid ester or sulfamine as well as a preparation method of pyridine azo disperse dye. The molecular structure of the compound is asshown in the following formula: (the formula is as shown in the description). The synthesis method comprises the following steps: taking 3-nitrobenzene sulfonyl chloride or 3-nitryl-4-substituted benzene sulfony chloride, alcohol, phenol or primary amine, 3-cyan-4-methyl-6-hydroxyl-2-pyrifone or 3-cyan-4-methyl-hydroxyl-N-alkyl-2-pyridone as raw materials, performing sulfonic acid esterificationor sulfonic amidation, performing nitro reduction and performing diazotization coupling to obtain a product. The product provided by the invention is novel in structure, simple in synthesis, low in cost and suitable for industrialized production.

FUSED HETEROCYCLIC DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME,AND MEDICINAL USE THEREOF

The present invention provides a compound useful as an agent for the prevention or treatment of a sex hormone-dependent disease or the like. That is, the present invention provides a fused heterocyclic derivative represented by the following general formula (I), a pharmaceutical composition containing the same, a medicinal use thereof and the like. In the formula (I), ring A represents 5-membered cyclic unsaturated hydrocarbon or 5-membered heteroaryl; RA represents halogen, alkyl, alkenyl, alkynyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like; ring B represents aryl or heteroaryl; RB represents halogen, alkyl, carboxy, alkoxy, carbamoyl, alkylcarbamoyl or the like; E1 and E2 represent an oxygen atom or the like; U represents a single bond or alkylene; X represents a group represented by Y, -SO2-Y, -O-(alkylene)-Y, -O-Z in which Y represents Z, amino or the like; Z represents cycloalkyl, heterocycloalkyl, aryl, heteroaryl or the like; or the like.