941670-16-2Relevant academic research and scientific papers
Synthesis of novel nitrogen containing naphtho[2,1-b]furan derivatives and investigation of their anti microbial activities
Nagaraja, Gundibasappa K.,Prakash, Gowdara K.,Kumaraswamy, Marlingaplara N.,Vaidya, Vijayavittala P.,Mahadevan, Kittappa M.
, p. 160 - 168 (2013/09/12)
Ethyl naphtho[2,1-b]furan-2-carboxylate has been prepared from 2-hydroxy-1- naphthaldehyde 1 and ethyl chloroacetate, which on further treatment with hydrazine hydrate gave naphtha[2,1-b]furan-2-carbohydrazide 3. The resulting compound 3 was treated with substituted aldehydes of 2-chloro-3-formylquinolines to give the Schiff base, which on treatment with chloro acetyl chloride gave the title compounds. The structure of the compounds has been confirmed by elemental analysis and spectral studies. The synthesized compounds were screened for their antibacterial and antifungal activities. ARKAT.
