94168-91-9

Upstream product

• 1354757-51-9 ethyl 2-(4-methylphenylsulfonamido)-3-oxo-3-phenylpropanoate 

Downstream Products

• 4113-71-7 α-Ethoxycarbonylamino-benzoylessigsaeure-ethylester 
• 4113-70-6 ethyl 2-oxo-5-phenyl-2,3-dihydrooxazole-4-carboxylate 
• 4845-13-0 2-oxo-5-phenyl-2,3-dihydro-oxazole-4-carboxylic acid 
• 1026234-44-5 2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-2-(1H-indol-3-yl)-ethyl]-5-phenyl-thiazole-4-carboxylic acid ethyl ester 
• 1027079-01-1 2-[(R)-1-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-2-(1H-indol-3-yl)-ethyl]-5-phenyl-oxazole-4-carboxylic acid ethyl ester 
• 168110-27-8 2-[(R)-1-Benzyloxycarbonylamino-2-(1H-indol-3-yl)-ethyl]-5-phenyl-thiazole-4-carboxylic acid ethyl ester 
• 1026742-70-0 2-[(R)-1-Benzyloxycarbonylamino-2-(1H-indol-3-yl)-ethyl]-5-phenyl-oxazole-4-carboxylic acid ethyl ester 
• 1027306-94-0 2-[(R)-1-Amino-2-(1H-indol-3-yl)-ethyl]-5-phenyl-1H-imidazole-4-carboxylic acid ethyl ester 
• 167982-85-6 2-[(R)-1-Amino-2-(1H-indol-3-yl)-ethyl]-5-phenyl-thiazole-4-carboxylic acid ethyl ester 
• 1028296-95-8 2-[(R)-1-Amino-2-(1H-indol-3-yl)-ethyl]-5-phenyl-oxazole-4-carboxylic acid ethyl ester 
• 94168-92-0 (rac.-1R,2S,3S,1'R)-N--1,2-epoxy-3-methyl-4,4-dioxyethylene-cyclohexane-1-carbonamide 
• 94168-92-0 (rac.-1R,2S,3S,1'S)-N--1,2-epoxy-3-methyl-4,4-dioxyethylene-cyclohexane-1-carbonamide 

Relevant academic research and scientific papers

A mild and efficient direct α-amination of β-dicarbonyl compounds using iodosobenzene and p-toluenesulfonamide catalyzed by perchlorate zinc hexahydrate

A direct α-amination of β-dicarbonyl compounds has been achieved by using iodosobenzene (PhIO) as an oxidant and p-toluenesulfonamide (TsNH 2) as an aminating reagent in the presence of a catalytic amount of perchlorate zinc hexahydrate. The present amination reaction proceeds quickly at rt (30 min needed for most tested substrates) to provide the corresponding α-N-tosylamido β-dicarbonyl compounds in high to excellent yields.