94191-19-2Relevant academic research and scientific papers
SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS
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, (2015/05/19)
The present invention relates to novel spiro-oxadiazoline compounds that are suitable as agonists or partial agonists of a7-nAChR, and pharmaceutical compositions of the same, methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering a spiro-oxadiazoline cx7-nAChR agonist or partial agonist, to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR
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, (2012/10/08)
Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.
CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR
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, (2011/07/30)
Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.
Chemistry of Thienopyridines. XXXI. A New Synthesis of Thienopyridine and Studies on Direct Substitution into Its Thiophene Ring
Klemm, L. H.,Louris, John N.
, p. 785 - 790 (2007/10/02)
Thienopyridine (1) is synthesized in 65percent overall yield for two steps which consist of addition of toluene-α-thiol to 2-ethynylpyridine plus vacuum pyrolysis of the addend (7).Cis and trans forms of 7 are described.Compound 1 undergoes (a) ele
