94209-86-6

Basic information

• Product Name: 3,6-di-(4-methoxyphenoxy)pyridazine
• Synonyms: 3,6-di-(4-methoxyphenoxy)pyridazine
• CAS NO: 94209-86-6
• Molecular Weight: 324.336
• Mol File: 94209-86-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3,6-di-(4-methoxyphenoxy)pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-di-(4-methoxyphenoxy)pyridazine(94209-86-6)
• EPA Substance Registry System: 3,6-di-(4-methoxyphenoxy)pyridazine(94209-86-6)

Safety Data

• Hazardous Substances Data: 94209-86-6(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 18063-93-9 dimethyl 1,4-dimethyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate 
• 141-30-0 3,6-dichlorpyridazine 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Dynamic Nucleophilic Aromatic Substitution of Tetrazines

A dynamic nucleophilic aromatic substitution of tetrazines (SNTz) is presented herein. It combines all the advantages of dynamic covalent chemistry with the versatility of the tetrazine moiety. Indeed, libraries of compounds or sophisticated molecular structures can be easily obtained, which are susceptible to post-functionalization by inverse electron demand Diels–Alder (IEDDA) reaction, which also locks the exchange. Additionally, the structures obtained can be disassembled upon the application of the right stimulus, either UV irradiation or a suitable chemical reagent. Moreover, SNTz is compatible with the imine chemistry of anilines. The high potential of this methodology has been proved by building two responsive supramolecular systems: A macrocycle that displays a light-induced release of acetylcholine; and a truncated [4+6] tetrahedral shape-persistent fluorescent cage, which is disassembled by thiols unless it is post-stabilized by IEDDA.

Synthesis of some 3,6-disubstituted pyridazines

Some novel 3-halo-6-(4-substituted-phenoxy)pyridazines and 3,6-di-(4- substituted-phenoxy)pyridazines were synthesized from 3,6-dichloropyridazine or 3,6-diiodopyridazine. 3,6-Diiodopyridazine was prepared from 3,6- dichloropyridazine using hydriodic acid/iodine monochloride.