94212-07-4Relevant academic research and scientific papers
Estrogen receptor β selective ligands: Discovery and SAR of novel heterocyclic ligands
Chesworth, Richard,Wessel, Matthew D.,Heyden, Lisa,Mangano, F. Michael,Zawistoski, Michael,Gegnas, Laura,Galluzzo, David,Lefker, Bruce,Cameron, Kimberly O.,Tickner, Jeanne,Lu, Bihong,Castleberry, Tessa A.,Petersen, Donna N.,Brault, Amy,Perry, Pia,Ng, Oicheng,Owen, Thomas A.,Pan, Lydia,Ke, Hua-Zhu,Brown, Thomas A.,Thompson, David D.,DaSilva-Jardine, Paul
, p. 5562 - 5566 (2007/10/03)
A series of ligands with varying heterocyclic cores and substituents that display a range of selectivity's (up to >100x) for ER-β over ER-α are reported.
Benzimidazole compounds and their use as estrogen agonists/antagonists
-
, (2008/06/13)
This invention relates to compounds, in particular benzimidazoles, that are useful as estrogen agonists and/or antagonists and pharmaceutical uses thereof. The present invention also relates to benzimidazoles that are selective for the ERβ receptor and pharmaceutical uses thereof.
BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS ESTROGEN AGONISTS/ANTAGONISTS
-
Page 73, (2010/02/05)
This invention relates to compounds, in particular benzimidazoles, that are useful as estrogen agonists and/or antagonists and pharmaceutical uses thereof. The present invention also relates to benzimidazoles that are selective for the ER? receptor and pharmaceutical uses thereof.
