942185-01-5 Usage
Description
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE is a heterocyclic organic compound that belongs to the pyrazolopyridines family. It is characterized by a pyrazole ring fused to a pyridine ring, with an amine group attached to the fifth carbon in the pyridine ring. This unique structure endows it with distinct chemical properties, making it a valuable component in the field of medicinal chemistry. It is widely recognized for its potential as an active intermediate in the development of pharmaceuticals and agrochemicals, where it contributes to the creation of potent bioactive molecules. However, it is essential to adhere to strict safety protocols when handling this compound to mitigate any associated risks.
Uses
Used in Pharmaceutical Industry:
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE is used as an active intermediate for the synthesis of various bioactive molecules. Its unique structure allows for the development of new drugs with potential therapeutic applications, making it a crucial component in the design and synthesis of novel pharmaceutical compounds.
Used in Agrochemical Industry:
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE is used as a key intermediate in the production of agrochemicals. Its chemical properties enable the creation of effective pesticides, herbicides, and other agricultural chemicals that can help improve crop yields and protect plants from pests and diseases.
Used in Medicinal Chemistry Research:
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE is used as a research compound for exploring its potential in medicinal chemistry. Its distinctive structure offers opportunities for investigating new chemical reactions and interactions, which could lead to the discovery of innovative therapeutic agents and drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 942185-01-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,1,8 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 942185-01:
(8*9)+(7*4)+(6*2)+(5*1)+(4*8)+(3*5)+(2*0)+(1*1)=165
165 % 10 = 5
So 942185-01-5 is a valid CAS Registry Number.
942185-01-5Relevant articles and documents
Development of 2, 4-diaminoquinazoline derivatives as potent PAK4 inhibitors by the core refinement strategy
Hao, Chenzhou,Huang, Wanxu,Li, Xiaodong,Guo, Jing,Chen, Meng,Yan, Zizheng,Wang, Kai,Jiang, Xiaolin,Song, Shuai,Wang, Jian,Zhao, Dongmei,Li, Feng,Cheng, Maosheng
, p. 1 - 13 (2017/03/16)
Upon analysis of the reported crystal structure of PAK4 inhibitor KY04031 (PAK4 IC50?=?0.790?μM) in the active site of PAK4, we investigated the possibility of changing the triazine core of KY04031 to a quinazoline. Using KY04031 as a starting
Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands
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Paragraph 0374-0375, (2013/03/26)
Substituted bicyclic aromatic carboxamide and urea compounds as vanilloid receptor ligands, pharmaceutical compositions containing these compounds, and a method of using these compounds in the treatment and/or inhibition of pain and further diseases and/or disorders mediated at least in part via the vanilloid receptor 1 (VR1/TRPV1).
POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS
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Page/Page column 249, (2008/06/13)
Disclosed are the ERK inhibitors of formula 1.0 and the pharmaceutically acceptable salts and solvates thereof. Q is a piperidine or piperazine ring that can have a bridge or a fused ring. The piperidine ring can have a double bond in the ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
