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Upstream product

• 540-38-5 p-Iodophenol 
• 24541-43-3 4-azidophenol 
• 88075-18-7 4-(2-(trimethylsilyl)ethynyl)phenol 
• 123-30-8 4-amino-phenol 
• 2200-91-1 4-ethynylphenol 

Relevant academic research and scientific papers

Thermally induced structural transformation of bisphenol-1,2,3-triazole polymers: Smart, self-extinguishing materials

Safer plastics: A novel class of polymers, termed bisphenol-1,2,3-triazole (BPT) polyarylates, was prepared by polycondensation chemistry. They exhibit high-performance and self-extinguishing properties as a result of their heterocyclic nature and a therm

Molecular cage-bridged plasmonic structures with well-defined nanogaps as well as the capability of reversible and selective guest trapping

Creating well-defined plasmonic hotspots with enormous field enhancements as well as the capability of selectively trapping targeted molecules into hotspots is of critical importance and a prerequisite for numerous plasmon-assisted applications, but it represents a great challenge. In this work, a robust molecular cage decorated with thioether moieties at the periphery was designed and synthesized. By using the synthesized cage as a linker, a series of molecular cage-bridged plasmonic structures with well-defined nanogaps (hotspots) were fabricated in an efficient and controllable fashion. It was found both experimentally and theoretically that the nanogaps of about 1.2 nm created by the molecular cage in the resultant plasmonic structures led to a strong plasmon coupling, thus inducing great field enhancement inside the nanogaps. More importantly, the embedded molecular cages endowed the formed hotspots with the capability of selectively trapping targeted molecules, offering huge opportunities for many emergent applications. As a demonstration, the hotspots constructed were used as a unique nanoreactor, and under mild conditions two types of plasmon-driven chemical transformation were successfully performed. All the results clearly indicate that the integration of the host-guest chemistry of the molecular cage with the plasmon-coupling effect of metal particles afforded a new class of plasmonic structures, showing great potential for facilitating a broad variety of plasmon-based applications.

Application of fragment screening and merging to the discovery of inhibitors of the mycobacterium tuberculosis cytochrome P450 CYP121

Pieces of the puzzle: The first fragment-based approach was used to target cytochrome P450 enzymes (CYPs) for drug development (see scheme). The experiments provide new insights into the binding site of the essential Mycobacterium tuberculosis CYP121 enzyme, and resulted in a promising novel lead compound based on fragment merging.

Bisphenol-1,2,3-triazole (BPT) epoxies and cyanate esters: Synthesis and self-catalyzed curing

Novel bisphenol-1,2,3-triazole (BPT) resins, including epoxy (DGE-BPT) and cyanate ester (BPTCE) systems, were prepared and used in curing chemistry with no added reagents or catalysts. The materials were characterized relative to conventional epoxies and