94224-71-2

Basic information

• Product Name: 1H-2-Benzopyran-3-carboxylic acid, 1-oxo-4-phenyl-, ethyl ester
• CAS NO: 94224-71-2
• Molecular Formula: C18H14O4
• Molecular Weight: 294.307
• Mol File: 94224-71-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran-3-carboxylic acid, 1-oxo-4-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran-3-carboxylic acid, 1-oxo-4-phenyl-, ethyl ester(94224-71-2)
• EPA Substance Registry System: 1H-2-Benzopyran-3-carboxylic acid, 1-oxo-4-phenyl-, ethyl ester(94224-71-2)

Safety Data

• Hazardous Substances Data: 94224-71-2(Hazardous Substances Data)

Upstream product

• 65-85-0 benzoic acid 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 85-52-9 2-Benzoylbenzoic acid 
• 685-87-0 Diethyl 2-bromomalonate 
• 22103-85-1 2-benzoylbenzoyl chloride 
• 17507-56-1 ethyl 2-diazo-2-(diethoxyphosphoryl)acetate 
• 94224-63-2 3-(2-Benzoyl-phenyl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid ethyl ester 

Downstream Products

• 37617-98-4 4-phenyl-3-isocoumarincarboxylic acid 

Relevant articles and documents

RhIII-Catalyzed Regioselective Preparation of 3-Hetero-Substituted Isocoumarins from Aryl Carboxylic Acids and Alkynes

An oxygen-mediated annulation reaction has been reported herein. Various 3-hetero-substituted isocoumarins were successfully prepared with high efficiency (yields up to 88 %) and good functional-group tolerance (35 examples) in the presence of a rhodium catalyst. A plausible mechanism has also been proposed that shows the high regioselectivity mostly likely originates from the electron-density difference between the alkynyl carbon atoms of the substrate.

Tetracyclic benzamide derivatives and methods of use thereof

The invention relates to Tetracyclic Benzamide Derivatives; compositions comprising a Tetracyclic Benzamide Derivative; and methods for treating or preventing an inflammatory disease, a reperfusion disease, an ischemic condition, renal failure, diabetes,

UNE SYNTHESE ORIGINALE ET INATTENDUE D'ISOCOUMARINES FONCTIONNELLES

Reaction of Ph3P=CH-COOEt with ortho benzoyl benzoic acid derivates offers an easy and surprising entry to functional isocoumarins via the thermal decomposition of the keto-ylide intermediates or by subsequent oxidation of the expected indenones.