942297-60-1

Usage

Uses

Used in Pharmaceutical Research:
Boc-Glycine is used as a building block in peptide synthesis for the development of certain drugs and pharmaceuticals. Its stability and ease of handling make it a popular choice in the field of organic chemistry.
Used in Peptide Synthesis:
In the synthesis of peptides, Boc-Glycine is employed as a key component, contributing to the creation of essential compounds for drug development.
Used as an Intermediate in Pharmaceutical Production:
Boc-Glycine is a useful intermediate in the production of various pharmaceutical compounds, facilitating the synthesis of a wide range of medications.
Used in Research Laboratories:
In research settings, Boc-Glycine is commonly utilized for the synthesis of peptides and other chemical compounds, supporting scientific exploration and innovation in the pharmaceutical industry.

Upstream product

• 856417-64-6 2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid 
• 129902-07-4 aspartic acid methyl ester hydrochloride 

Relevant academic research and scientific papers

Multifunctional diamine AGE/ALE inhibitors with potential therapeutical properties against Alzheimer's disease

An important part of pathogenesis of Alzheimer's disease (AD) is attributed to the contribution of AGE (Advanced Glycation Endproducts) and ALE (Advanced Lipid peroxidation Endproducts). In order to attenuate the progression of AD, we designed a new type of molecules that consist of two trapping parts for reactive carbonyl species (RCS) and reactive oxygen species (ROS), precursors of AGE and ALE, respectively. These molecules also chelate transition metals, the promoters of ROS formation. In this paper, synthesis of the new AGE/ALE inhibitors and evaluation of their physicochemical and biological properties (carbonyl trapping capacity, antioxidant activity, Cu2+-chelating capacity, cytotoxicity and protective effect against in?vitro MGO-induced apoptosis in the model AD cell-line PC12) are described. It is found that compounds 40b and 51e possess promising therapeutic potentials for treating AD.

Heteroarylpyrrolopyridinones active as kinase inhibitors

Compounds represented by formula (I) wherein A, R1, R2, R3, R4, R5 and R6 are as defined in the specification or a pharmaceutically acceptable salt or solvate thereof, compositions thereof,