942318-16-3

Basic information

• Product Name: tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]phenyl}pyridin-2-yl)-2-phenylethyl]carbamate
• Synonyms: tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]phenyl}pyridin-2-yl)-2-phenylethyl]carbamate
• CAS NO: 942318-16-3
• Molecular Weight: 447.534
• Mol File: 942318-16-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]phenyl}pyridin-2-yl)-2-phenylethyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]phenyl}pyridin-2-yl)-2-phenylethyl]carbamate(942318-16-3)
• EPA Substance Registry System: tert-butyl N-[(1S)-1-(4-{4-[(methoxycarbonyl)amino]phenyl}pyridin-2-yl)-2-phenylethyl]carbamate(942318-16-3)

Safety Data

• Hazardous Substances Data: 942318-16-3(Hazardous Substances Data)

Upstream product

• 1589-82-8 phenylmagnesium bromide 
• 180748-31-6 1-(4-chloropyridin-2-yl)-2-phenylethan-1-amine 
• 872459-77-3 1-(4-chloropyridin-2-yl)-2-phenylethan-1-one 
• 942318-13-0 tert-butyl N-[-1-(4-chloropyridin-2-yl)-2-phenylethyl]carbamate 
• 24484-93-3 4-Chloro-pyridine-2-carboxylic acid methyl ester 
• 850567-96-3 (4-((methoxycarbonyl) amino)phenyl)boronic acid 
• 942318-14-1 tert-butyl N-[(1S)-1-(4-chloropyridin-2-yl)-2-phenylethyl]carbamate 

Downstream Products

• 942318-15-2 methyl N-(4-{2-[(1S)-1-amino-2-phenylethyl]pyridin-4-yl}phenyl)carbamate 

Relevant articles and documents

Orally bioavailable pyridine and pyrimidine-based Factor XIa inhibitors: Discovery of the methyl N-phenyl carbamate P2 prime group

Pyridine-based Factor XIa (FXIa) inhibitor (S)-2 was optimized by modifying the P2 prime, P1, and scaffold regions. This work resulted in the discovery of the methyl N-phenyl carbamate P2 prime group which maintained FXIa activity, reduced the number of H