94243-24-0Relevant academic research and scientific papers
Reinvestigation of the reaction of 3-substituted 1,2,4-triazines with nitronate anions: unexpected behavior of 3-(2-ethoxyphenyl)-1,2,4-triazine in the reaction with anions of nitroalkanes
Mojzych, Mariusz,Bernat, Zofia,Karczmarzyk, Zbigniew
, p. 968 - 977 (2019/11/14)
[Figure not available: see fulltext.] 3-Substituted 1,2,4-triazines easily react with nitronate anions to replace hydrogen atom in the position C-5 according to nucleophilic substitution mechanism and form appropriate oximes of 5-formyl- or 5-acyl-1,2,4-t
Synthesis and biological activity evaluation of Schiff bases of 5-acyl-1,2,4-triazine
Mojzych, Mariusz,Sebela, Marek
, p. 300 - 305 (2015/05/27)
A simple and general method has been developed for the synthesis of various Schiff bases (oximes, hydrazones, semicarbazones and thiosemicarbazones) derived from 5-acyl-1,2,4-triazines. Some of the new synthesized Schiff bases were tested for biological a
Antiviral activity evaluation of pyrazolo[4,3-e][1,2,4]triazines
Mojzych, Mariusz
scheme or table, p. 698 - 702 (2012/07/01)
The main purpose of this study is to screen synthesized pyrazolo[4,3- e][1,2,4]triazine derivatives for their antiviral activity against a panel of DNA and RNA viruses. Minimum cytotoxic and minimum virus-inhibitory concentrations of these compounds were
Enantioselective reduction of 5-acyl-1,2,4-triazines and their oximes by baker's yeast [1]
Rykowski,Lipinska,Guzik,Adamiuk,Olender
, p. 69 - 76 (2007/10/03)
Variously substituted 5-acyl-1,2,4-triazines 4a-d were regioselectively synthesized through a sequence involving nucleophilic acylation of 1,2,4-triazines 1a-b with nitronate anions 2a-c followed by hydrolysis of the oximes 3a-d thus formed, by sodium hyd
REACTION OF 1,2,4-TRIAZINES WITH NITRONATE ANIONS, DIRECT NUCLEOPHILIC ACYLATION OF 1,2,4-TRIAZINES
Rykowski, A.,Makosza, M.
, p. 4795 - 4796 (2007/10/02)
Nitronate anions replace 5-hydrogen atom in a variety of 3-substituted 1,2,4-triazine derivatives giving oximes of 5-formyl and 5-acyl 1,2,4-triazines.
