942485-79-2

Upstream product

• 32981-86-5 10-deacetylbaccatin III 
• 994-30-9 triethylsilyl chloride 
• 160161-59-1 N-debenzoyl-N-Boc-3'-dephenyl-3'-isobutyldocetaxel 
• 942485-77-0 C₆₅H₇₇NO₁₉ 
• 194864-02-3 C-7,C-10-dibenzyloxycarbonyl-10-deacetyl baccatin III 
• 942485-78-1 C₅₃H₈₅NO₁₄Si₂ 

Downstream Products

• 942485-80-5 C₅₃H₈₇NO₁₄Si₂ 
• 942485-81-6 C₅₅H₈₉NO₁₅Si₂ 
• 849213-14-5 C₄₃H₆₁NO₁₅ 

Relevant academic research and scientific papers

TAXANE AND ABEO-TAXANE ANALOGS

The present application discloses new taxane analogs, intermediates and methods for producing them. The present application is also directed to pharmaceutical formulations comprising abeo-taxanes and methods of treating cancer with the abeo-taxanes.

NOVEL COMPOUNDS AND METHODS FOR FORMING TAXANES AND USING THE SAME

The present invention is broadly directed to novel compounds useful for the synthesis of biologically active compounds. More particularly, the present embodiments disclosed herein relate to novel side chains, that when coupled to a taxane, are useful for the synthesis of pharmaceutically useful taxanes. Methods of forming the novel side chains and coupling them to hindered alcohols, namely taxanes resulting in useful esters are also disclosed. Various taxanes compounds are known to exhibit anti-tumor activity.