942606-10-2Relevant academic research and scientific papers
Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis
Brown, Michael J.,Clarkson, Guy J.,Inglis, Graham G.,Shipman, Michael
supporting information; experimental part, p. 1686 - 1689 (2011/05/06)
An efficient two-step synthesis of a wide range of 3-methylene-1,2- diazetidines has been developed through application of a Cu(I)-catalyzed 4-exo ring closure. The double bond of this new class of strained heterocycle can be functionalized in a stereocon
The asymmetric synthesis of α-substituted α-methyl and α-phenyl phosphonic acids: Design, carbanion geometry, reactivity and preparative aspects of chiral alkyl bicyclic phosphonamides
Bennani, Youssef L.,Hanessian, Stephen
, p. 13837 - 13866 (2007/10/03)
The design, preparation, structural and spectroscopic analyses of topologically unique and enantiomerically pure alkyl phosphonamides are described. In the case of α-ethyl and α-benzyl phosphonamides, the geometry of both the secondary and tertiary carbanions was determined to be planar through deprotonation/deuteration/alkylation experiments. Stereoselective alkylations of such systems proceeded in good yields and with high diastereoselectivities. The resulting α,α-alkylated phosphonamides were hydrolyzed to give the corresponding α,α-alkyl phosphonic acids with high degrees of enantiomeric purity.
Synthesis and characterization of both enantiomers of a chiral C60 derivative with C2 symmetry
Maggini,Scorrano,Bianco,Toniolo,Prato
, p. 2845 - 2846 (2007/10/02)
The addition of chiral diamines to C60 allows the synthesis of the two enantiomers of a chiral C60 derivative with C2 symmetry. The circular dichroism spectra of the two isomers show a very intense chirospectroscopic response.
