942613-49-2Relevant academic research and scientific papers
Quinolinyl- and phenantridinyl-acetamides as bradykinin B1 receptor antagonists
éles, János,Beke, Gyula,Vágó, István,Bozó, éva,Huszár, József,Tarcsay, ákos,Kolok, Sándor,Schmidt, éva,Vastag, Mónika,Hornok, Katalin,Farkas, Sándor,Domány, Gy?rgy,Keser, Gy?rgy M.
, p. 3095 - 3099 (2012/06/17)
A new series of quinolinyl- and phenantridinyl-acetamides were synthesizer and evaluated against bradykinin B1 receptor. In vitro metabolic stability data were reported for the key compounds.The analgesic effect of compound 20 from the phenantridine series was proved in-vivo.
NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS
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Page/Page column 26-27, (2008/06/13)
The present invention relates to new phenanthridine derivatives of formula (I) wherein R1 is hydrogen atom or C1-C4 alkyl group; R2 is selected from (1) hydrogen atom; with the proviso that R1 and Rs
