943153-22-8

Basic information

• Product Name: (5-CHLORO-2-METHOXYPYRIDIN-3-YL)BORONIC ACID
• Synonyms: (5-CHLORO-2-METHOXYPYRIDIN-3-YL)BORONIC ACID;5-CHLORO-2-METHOXY-PYRIDINE-3-BORONIC ACID;5-chloro-2-Methoxypyridin-3-yl-3-boronic acid
• CAS NO: 943153-22-8
• Molecular Formula: C₆H₇BClNO₃
• Molecular Weight: 187.39
• Product Categories: Boronic Acid;pyridine series
• Mol File: 943153-22-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 148-152°C
• Boiling Point: 353.1 °C at 760 mmHg
• Flash Point: 167.3 °C
• Appearance: /
• Density: 1.4 g/cm³
• Refractive Index: 1.545
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.93±0.58(Predicted)
• CAS DataBase Reference: (5-CHLORO-2-METHOXYPYRIDIN-3-YL)BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (5-CHLORO-2-METHOXYPYRIDIN-3-YL)BORONIC ACID(943153-22-8)
• EPA Substance Registry System: (5-CHLORO-2-METHOXYPYRIDIN-3-YL)BORONIC ACID(943153-22-8)

Safety Data

• Hazardous Substances Data: 943153-22-8(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

5-Chloro-2-methoxypyridine-3-boronic Acid is a useful research chemical compound used in the preparation of triazine derivatives as inhibitors of phosphodiesterases for treating CNS disorders, metabolic disorders, and other diseases.

InChI:InChI=1/C6H7BClNO3/c1-12-6-5(7(10)11)2-4(8)3-9-6/h2-3,10-11H,1H3

Downstream Products

• 943153-23-9 [4-(5-chloro-2-methoxypyridin-3-yl)-3-trifluoromethoxy-benzyl]-carbamic acid-tert-butyl ester 
• 943153-34-2 [4-(5-chloro-2-methoxy-pyridin-3-yl)-3-methoxy-benzyl]-carbamic acid tert-butyl ester 
• 943153-26-2 (R)-1-[4-(5-chloro-2-methoxypyridin-3-yl)-phenyl]-ethylamine 

Relevant articles and documents

IMIDAZO [1,2-B] PYRIDAZINE AND IMIDAZO [4,5-B] PYRIDINE DERIVATIVES AS JAK INHIBITORS

New imidazo[1,2-b]pyridazine and imidazo[4,5-b]pyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).