94328-67-3Relevant academic research and scientific papers
HETEROCYCLIC COMPOUNDS AND USES THEREOF
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Paragraph 0439, (2021/07/31)
Provided herein are novel heterocyclic compounds, for example, compounds having Formula I, I-P, II, lI-P, or III. Also provided herein are pharmaceutical compositions comprising the compounds and methods of using the same, for example, in inhibiting aldehyde dehydrogenases and/or for treating various cancers, cancer metastasis, type 2 diabetes, pulmonary arterial hypertension (PAH) or neointimal hyperplasia (NIH).
Selectivity of N-versus O-alkylation in Mitsunobu reactions with various quinolinols and isoquinolinols
Hartung, Ryan E.,Wall, Mark C.,Lebreton, Sylvain,Smrcina, Martin,Patek, Marcel
, p. 1305 - 1313 (2017/07/18)
Reacting quinolinols and isoquinolinols under Mitsunobu conditions can give rise to N-alkylated products in addition to the normally desired O-alkylated structures. An in-depth study of how the solvent, reagent equivalents, position of the quinoline/isoqu
