943321-95-7

Basic information

• Product Name: 1,1-dimethylethyl [3-({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}amino)-3-oxo-2-phenylpropyl]carbamate
• Synonyms: 1,1-dimethylethyl [3-({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}amino)-3-oxo-2-phenylpropyl]carbamate
• CAS NO: 943321-95-7
• Molecular Weight: 681.631
• Mol File: 943321-95-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl [3-({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}amino)-3-oxo-2-phenylpropyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl [3-({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}amino)-3-oxo-2-phenylpropyl]carbamate(943321-95-7)
• EPA Substance Registry System: 1,1-dimethylethyl [3-({4-bromo-5-[1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}amino)-3-oxo-2-phenylpropyl]carbamate(943321-95-7)

Safety Data

• Hazardous Substances Data: 943321-95-7(Hazardous Substances Data)

Upstream product

• 26250-90-8 (3R)-benzyl-3-(tert-butoxycarbonyl)amino-propanoic acid 
• 942919-24-6 1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo-[2,3-b]pyridine 
• 1159682-82-2 C₁₈H₂₀Br₂N₂O₃S 

Downstream Products

• 1159682-85-5 C₂₅H₂₅BrN₄O₃S 

Relevant articles and documents

Discovery of 5-pyrrolopyridinyl-2-thiophenecarboxamides as potent AKT kinase inhibitors

A pyrrolopyridinyl thiophene carboxamide 7 was discovered as a tractable starting point for a lead optimization effort in an AKT kinase inhibition program. SAR studies aided by a co-crystal structure of 7 in AKT2 led to the identification of AKT inhibitor