943326-46-3Relevant academic research and scientific papers
Remarkable drug-release enhancement with an elimination-based AB3 self-immolative dendritic amplifier
Sagi, Amit,Segal, Ehud,Satchi-Fainaro, Ronit,Shabat, Doron
, p. 3720 - 3727 (2008/02/07)
Self-immolative dendritic prodrugs, activated through a single catalytic reaction by a specific enzyme, could offer significant advantages in inhibition of tumor growth relative to monomeric prodrug, especially if the targeted or secreted enzyme exists at
