94348-72-8Relevant academic research and scientific papers
Switching the reactivity of dihydrothiopyran-4-one with aldehydes by aqueous organocatalysis: Baylis-Hillman, aldol, or aldol condensation reactions
Abaee, M. Saeed,Mojtahedi, Mohammad M.,Pasha, Ghasem F.,Akbarzadeh, Elahe,Shockravi, Abbas,Mesbah, A. Wahid,Massa, Werner
scheme or table, p. 5282 - 5285 (2011/12/14)
An aqueous medium containing catalytic amounts of a tertiary amine was employed to direct the chemoselectivity of the reaction of aldehydes with 1a. With DBU, 2 was formed at room temperature as a rare exemplary of Baylis-Hillman reactions in heterocyclic
Rate acceleration of the Baylis-Hillman reaction in polar solvents (water and formamide). Dominant role of hydrogen bonding, not hydrophobic effects, is implicated
Aggarwal, Varinder K.,Dean, David K.,Mereu, Andrea,Williams, Richard
, p. 510 - 514 (2007/10/03)
A substantial acceleration of the Baylis-Hillman reaction between cyclohexenone and benzaldehyde has been observed when the reaction is conducted in water. Several different amine catalysts were tested, and as with reactions conducted in the absence of so
Simple method for α-alkylation of α,β-unsaturated enones through the Michael addition
Hwu, Jih Ru,Hakimelahi, Gholam H.,Chou, Ching-Tai
, p. 6469 - 6472 (2007/10/02)
Treatment of enones and Michael acceptors with a catalytic amount of 1,8-diazabicyclo[5.4.0]undec-7-ene in 1,3-dimethyl-2-imidazolidinone at 185 °C afforded the corresponding α-substituted enones in good yields.
Tandem Conjugate Addition-Aldol Reactions Employing 9-(Phenylseleno)-9-borabicyclononane: A Novel Method for Effecting Formal Aldol Condensations at the α-Carbon of α,β-Unsaturated Ketones
Leonard, William R.,Livinghouse, Tom
, p. 730 - 732 (2007/10/02)
The title compound has been shown to undergo conjugate addition to a variety of α,β-unsaturated ketones to afford β-seleno boron enolates which are convertable to unsaturated ketols upon treatment with aldehydes and subsequent oxidative elimination.
