94348-98-8

Upstream product

• 110-57-6 trans-1,4-dichlorobut-2-ene 
• 1576-37-0 N-benzyl-p-toluenesulfonamide 

Downstream Products

• 94349-00-5 Acetic acid (E)-4-[benzyl-(toluene-4-sulfonyl)-amino]-but-2-enyl ester 
• 94349-10-7 (E)-(4S,5R)-4,5-Bis-benzyloxy-6-[benzyl-(toluene-4-sulfonyl)-amino]-hex-2-enoic acid ethyl ester 
• 94349-13-0 N-Benzyl-N-[(2R,3R)-2,3-bis-benzyloxy-3-((2S,3R)-3-hydroxymethyl-oxiranyl)-propyl]-4-methyl-benzenesulfonamide 
• 94349-05-0 N-Benzyl-N-((2R,3R)-2,3-bis-benzyloxy-4-phenylsulfanyl-butyl)-4-methyl-benzenesulfonamide 
• 94349-12-9 N-Benzyl-N-((E)-(2R,3S)-2,3-bis-benzyloxy-6-hydroxy-hex-4-enyl)-4-methyl-benzenesulfonamide 
• 94349-09-4 N-Benzyl-N-((2R,3R)-2,3-bis-benzyloxy-4-oxo-butyl)-4-methyl-benzenesulfonamide 
• 94349-08-3 N-Benzyl-N-((2R,3S)-2,3-bis-benzyloxy-4-hydroxy-butyl)-4-methyl-benzenesulfonamide 
• 94349-04-9 N-Benzyl-N-((2R,3R)-2,3-dihydroxy-4-phenylsulfanyl-butyl)-4-methyl-benzenesulfonamide 
• 94349-03-8 N-Benzyl-N-((2R,3R)-3-hydroxymethyl-oxiranylmethyl)-4-methyl-benzenesulfonamide 
• 94349-01-6 N-benzyl-N-[(2E)-4-hydroxy-2-butenyl]-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

Novel method for construction of tetrahydro-1-benzazepine and tetrahydro-2-benzazepine based on 7-endo selective Friedel-Crafts cyclization of vinyloxirane

The 7-endo Friedel-Crafts cyclization of vinyloxiranes, which have a nitrogen atom at the linker between the aromatic ring and the epoxide, was found to proceed regio- and stereoselectively to afford polyfunctional tetrahydro-1-benzazepine and tetrahydro-

Enantioselective Synthesis of Swainsonine, a Trihydroxylated Indolizidine Alkaloid

A total synthesis of (-)-swainsonine in 21 steps and 6.6percent overall yield starting from trans-1,4-dichloro-2-butene and N-benzyl-p-toluenesulfonamide is described.The synthesis employs the methodology of the Masamune/Sharpless approach to polyhydroxylated natural products.