94352-93-9Relevant academic research and scientific papers
Synthesis of substituted quinolines by the electrophilic cyclization of n-(2-alkynyl)anilines
Zhang, Xiaoxia,Yao, Tuanli,Campo, Marino A.,Larock, Richard C.
supporting information; experimental part, p. 1177 - 1187 (2010/04/02)
A wide variety of substituted quinolines are readily synthesized under mild reaction conditions by the 6-endo-dig electrophilic cyclization of N-(2-alkynyl)anilines by ICl, I2, Br2, PhSeBr, and p-O2NC6H4SCl. The reaction affords 3-halogen-, selenium- and sulfur-containing quinolines in moderate to good yields in the presence of various functional groups. Analogous quinolines bearing a hydrogen in the 3-position have been synthesized by the Hg(OTf)2-catalyzed ring closure of these same alkynylanilines.
Synthesis of Five-membered Lactams by α-Carbamoyl Radical Cyclisations
Sato, Tatsunori,Wada, Yasuko,Nishimoto, Mami,Ishibashi, Hiroyuki,Ikeda, Masazumi
, p. 879 - 886 (2007/10/02)
Free-radical cyclisation of N-allyl-α-carbamoyl radicals generated by tributyltin radical-mediated cleavage of carbon-chlorine or carbon-sulphur bonds has been studied in some detail.The radicals substituted at the α position by methylthio (phenylthio), c
