94353-40-9Relevant articles and documents
Rhodium-Catalyzed Annulative Coupling Using Vinylene Carbonate as an Oxidizing Acetylene Surrogate
Ghosh, Koushik,Nishii, Yuji,Miura, Masahiro
, p. 11455 - 11460 (2019/12/02)
Transition-metal-catalyzed C-H activation and subsequent oxidative cyclization with alkynes has been a powerful tool for the synthesis of polycyclic aromatic compounds. Despite the substantial progress in this field, it is still a significant challenge to establish synthetic methodologies for the construction of nonsubstituted vinylene-fused aromatics. We herein report a Rh(III)-catalyzed C-H/N-H annulation with vinylene carbonate as an acetylene surrogate. Vinylene carbonate also acts as an internal oxidant to regenerate the Rh(III) species in situ; thus, no external oxidant is required to trigger the oxidative annulation. This protocol is applicable to the direct synthesis of various N-heteroaromatics.
192. Synthese von 2,3-unsubstituierten, N-acylierten Indolen durch sigmatrope-Umlagerung von O-Vinyl-N-phenylhydroxylaminderivaten
Martin, Pierre
, p. 1647 - 1649 (2007/10/02)
Treatment of N-phenylhydroxamic acids with vinylacetate in the presence of Li2PdCl4 affords 2,3-unsubstituted N-acylindoles via hetero-Cope-rearrangement of the intermediate N-phenyl-O-vinylhydroxylamine derivatives.