94356-26-0 Usage
Description
Piceatannol 3'-O-glucoside is a bioactive compound found in Rhubarb, known for its ability to activate endothelial nitric oxide (NO) synthase by inhibiting arginase activity. It exhibits potent inhibitory effects against arginase I and arginase II with IC50 values of 11.22 μM and 11.06 μM, respectively.
Uses
Used in Pharmaceutical Industry:
Piceatannol 3'-O-glucoside is used as a therapeutic agent for promoting endothelial nitric oxide (NO) production, which plays a crucial role in various physiological processes, including vasodilation, platelet aggregation, and neurotransmission. Its ability to inhibit arginase activity makes it a potential candidate for the treatment of cardiovascular diseases and other conditions related to NO dysregulation.
Used in Nutraceutical Industry:
Piceatannol 3'-O-glucoside is used as a dietary supplement for enhancing vascular health and promoting overall well-being. Its NO-boosting properties can contribute to improved blood flow, reduced inflammation, and better cardiovascular function.
Used in Cosmetic Industry:
Piceatannol 3'-O-glucoside is used as an active ingredient in skincare products for its potential anti-aging and skin health benefits. Piceatannol 3'-O-glucoside's ability to modulate nitric oxide levels may contribute to improved skin elasticity, reduced wrinkles, and enhanced skin barrier function.
Check Digit Verification of cas no
The CAS Registry Mumber 94356-26-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,3,5 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 94356-26:
(7*9)+(6*4)+(5*3)+(4*5)+(3*6)+(2*2)+(1*6)=150
150 % 10 = 0
So 94356-26-0 is a valid CAS Registry Number.
94356-26-0Relevant articles and documents
Scalable Total Synthesis of Piceatannol-3′-O-β-d-glucopyranoside and the 4′-Methoxy Congener Thereof: An Early Stage Glycosylation Strategy
Chen, Lei,Li, Jianfeng,Wang, Xiaoting,Zhang, Rong-Ping
, (2021/11/04)
Scalable syntheses of piceatannol-3'-O-β-D-glucopyranoside and the 4'-methoxy congener thereof were achieved. This route features an early implemented Fischer-like glycosylation reaction, a regioselective iodination of phenolic glycoside under strongly acidic conditions, a highly telescoped route to access the styrene derivative, and a key Mizoroki.Heck reaction to render the desired coupled products in high overall yield.