943587-56-2Relevant academic research and scientific papers
Enantioselective Synthesis of Pyrrole-Fused Piperazine and Piperazinone Derivatives via Ir-Catalyzed Asymmetric Allylic Amination
Zhuo, Chun-Xiang,Zhang, Xiao,You, Shu-Li
, p. 5307 - 5310 (2016)
Ir-catalyzed intramolecular asymmetric allylic amination reaction of pyrrole derivatives was achieved. The pyrrole-fused piperazine and piperazinone derivatives could be easily accessed from the pyrrole-tethered allylic carbonates in good yields and enant
Asymmetric annulation toward pyrrolopip erazinones: Concise enantioselective syntheses of pyrrole alkaloid natural products
Trost, Barry M.,Dong, Guangbin
, p. 2357 - 2359 (2007)
A novel Pd-catalyzed asymmetric annulation between 5-bromopyrrole-2- carboxylate esters and vinyl aziridines has been developed to efficiently construct pyrrolopiperazinones, which can serve as key intermediates in the enantioselective syntheses of pyrrol
Palladium-catalyzed dynamic kinetic asymmetric transformations of vinyl aziridines with nitrogen heterocycles: Rapid access to biologically active pyrroles and indoles
Trost, Barry M.,Osipov, Maksim,Dong, Guangbin
supporting information; experimental part, p. 15800 - 15807 (2011/02/21)
We report that nitrogen heterocycles can serve as competent nucleophiles in the palladium-catalyzed dynamic kinetic asymmetric alkylation of vinyl aziridines. The resulting alkylated products were obtained with high regio-, chemo-, and enantioselectivity.
