943600-47-3Relevant academic research and scientific papers
o-naphthalenedicarboxaldehyde derivative of 7′-aminonaltrindole as a selective δ-opioid receptor affinity label
Haris, Sarika Prabhu,Zhang, Yan,Le Bourdonnec, Bertrand,McCurdy, Christopher R.,Portoghese, Philip S.
, p. 3392 - 3396 (2007)
Incorporation of a naphthalene-dialdehyde moiety into the δ antagonist, 6′-aminonaltrindole afforded a potent, selective, irreversible δ-agonist 1. However, flow cytometry studies revealed no time-dependent specific fluorescence, suggesting that both Lys2
Affinity labels as tools for the identification of opioid receptor recognition sites
Portoghese, Philip S.,El Kouhen, Rachid,Law, Ping Y.,Loh, Horace H.,Le Bourdonnec, Bertrand
, p. 191 - 196 (2007/10/03)
Affinity labels have proven to be useful tools in opioid research. We review experiments carried out with the μ opioid receptor affinity label, β-funaltrexamine (2), that support the concept of different recognition sites for μ opioid agonists and antagon
