943726-01-0

Basic information

• Product Name: Propargyl-PEG3-Ms
• Synonyms: Propargyl-PEG3-Ms
• CAS NO: 943726-01-0
• Molecular Formula: C₈H₁₄O₅S
• Molecular Weight: 222.26
• Mol File: 943726-01-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Propargyl-PEG3-Ms(CAS DataBase Reference)
• NIST Chemistry Reference: Propargyl-PEG3-Ms(943726-01-0)
• EPA Substance Registry System: Propargyl-PEG3-Ms(943726-01-0)

Safety Data

• Hazardous Substances Data: 943726-01-0(Hazardous Substances Data)

Usage

Description

Propargyl-PEG3-Ms is a crosslinking reagent with a propargyl group and a mesyl group. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.

Upstream product

• 34604-52-9 diethylene glycol dimesylate 
• 107-19-7 propargyl alcohol 

Downstream Products

• 1609429-21-1 2-(2-((1-(3-methoxycarbonyl-4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)methoxy)ethoxy)ethylmethanesulfonate 
• 1609429-14-2 methyl 5-(4-((2-(2-fluoroethoxy)ethoxy)methyl)-1H-1,2,3-triazol-1-yl)-2-methoxybenzoate 
• 1609429-17-5 5-(4-((2-(2-fluoroethoxy)ethoxy)methyl)-1H-1,2,3-triazol-1-yl)-2-methoxybenzoic acid 
• 1609428-82-1 N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-5-(4-((2-(2-fluoroethoxy)ethoxy)methyl)-1H-1,2,3-triazol-1-yl)-2-methoxybenzamide 

Relevant articles and documents

Synthesis and structure-activity relationship studies of conformationally flexible tetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands

Two novel classes of compounds targeting the sigma-2 (σ2) receptor were synthesized, and their bioactivities to binding σ1 and σ2 receptors were measured. Four novel triazole carboxamide analogues, 24d, 24e, 24f, and 39c, demonstrated high affinity and selectivity for the σ2 receptor. These data suggest 11C-labeled versions of these compounds may be potential σ2-selective radiotracers for imaging the proliferative status of solid tumors.