943726-04-3Relevant articles and documents
A benzenesulfonamide derivative as a novel PET radioligand for CXCR4
Goodman, Mark M.,Liang, Zhongxing,Oum, Yoon Hyeun,Shetty, Dinesh,Shim, Hyunsuk,Voll, Ronald J.,Yoon, Younghyoun
, (2020)
CXCR4 is involved in various diseases such as inflammation, tumor growth, and cancer metastasis through the interaction with its natural endogenous ligand, chemokine CXCL12. In an effort to develop imaging probes for CXCR4, we developed a novel small mole
METHYLSULFONAMIDE DERIVATIVES AND USES RELATED THERETO
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Page/Page column 73-74, (2017/02/28)
This disclosure relates to methylsulfonamide derivatives and uses as imaging agents and other uses related to CXCR4 inhibition. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein, derivative
An efficient F-18 labeling method for PET study: Huisgen 1,3-dipolar cycloaddition of bioactive substances and F-18-labeled compounds
Sirion, Uthaiwan,Kim, Hee Jun,Lee, Jae Hak,Seo, Jai Woong,Lee, Byoung Se,Lee, Sang Ju,Oh, Seung Jun,Chi, Dae Yoon
, p. 3953 - 3957 (2008/02/04)
The Cu(I)-catalyzed, 1,3-dipolar cycloaddition reaction was applied successfully to the synthesis of small, F-18-labeled biomolecules, and an optimal condition was developed for one-pot, two-step reaction without any interim purifications. This technique was employed in various F-18-labeled, 1,2,3-triazole syntheses with high radiochemical yield.