943864-73-1Relevant articles and documents
Synthesis and biological evaluation of novel isopropanolamine derivatives as non-peptide human immunodeficiency virus protease inhibitors
Zhou, Lijun,Yang, Qingang,Wang, Yong,Hu, Youhong,Luo, Xiaomin,Bai, Donglu,Li, Shukun
experimental part, p. 1147 - 1152 (2009/09/25)
Novel potential human immunodeficiency virus (HIV) protease inhibitors were designed by a combination of nelfinavir and amprenavir motifs. The designed compounds were prepared by a facile synthetic route and their stereochemistry was further confirmed by
Sulfonamide-based compositions and methods
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, (2008/06/13)
Methods are provided for using 2-hydroxy-3-aminopropylsulfonamides to mimic peptides and to modulate the chemical and/or biological activity of enzymes, particularly proteolytic enzymes. Also provided are compositions comprising the sulfonamides in admixt