2424-04-6

Usage

InChI:InChI=1/C7H15N/c1-4-5-8-6-7(2)3/h4,7-8H,1,5-6H2,2-3H3

Upstream product

• 78-77-3 Isobutyl bromide 
• 107-11-9 1-amino-2-propene 
• 254428-45-0 N-(2-methylpropylidene)-2-propenyl-1-amine 
• 4344-71-2 2-methyl-N-prop-2-enylpropanamide 
• 69882-86-6 N-allyl-2-methylpropan-1-imine 
• 78-84-2 isobutyraldehyde 
• 78-81-9 isobutylamine 
• 106-95-6 allyl bromide 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 40093-10-5 C₁₆H₂₂ClN₃O 
• 52317-49-4 1-Allyl-3-(4-chloro-2-methyl-phenyl)-1-isobutyl-thiourea 
• 25675-91-6 Allyl-isobutyl-dithiocarbamic acid 2,4-dinitro-phenyl ester 
• 943864-73-1 N-allyl-N-isobutyl-4-nitrobenzenesulfonamide 

Relevant academic research and scientific papers

Selective hydrosilylation of N-allylimines using a (3-iminophosphine)palladium precatalyst

Hydrosilylation utilizing a (3-iminophosphine)palladium catalyst leads to the selective reduction of the imine unit of allylimines. Successful reduction of twenty-five different substituted aromatic and alkyl allylimines demonstrated the scope and selecti

Sequence-defined polymers via orthogonal allyl acrylamide building blocks

Biological systems have long recognized the importance of macromolecular diversity and have evolved efficient processes for the rapid synthesis of sequence-defined biopolymers. However, achieving sequence control via synthetic methods has proven to be a difficult challenge. Herein we describe efforts to circumvent this difficulty via the use of orthogonal allyl acrylamide building blocks and a liquid-phase fluorous support for the de novo design and synthesis of sequence-specific polymers. We demonstrate proof-of-concept via synthesis and characterization of two sequence-isomeric 10-mer polymers. 1H NMR and LCMS were used to confirm their chemical structure while tandem MS was used to confirm sequence identity. Further validation of this methodology was provided via the successful synthesis of a sequence-specific 16-mer polymer incorporating nine different monomers. This strategy thus shows promise as an efficient approach for the assembly of sequence-specific functional polymers.

Synthesis and biological evaluation of novel isopropanolamine derivatives as non-peptide human immunodeficiency virus protease inhibitors

Novel potential human immunodeficiency virus (HIV) protease inhibitors were designed by a combination of nelfinavir and amprenavir motifs. The designed compounds were prepared by a facile synthetic route and their stereochemistry was further confirmed by

Highly unusual conversion of 1-alkyl-2-(bromomethyl)aziridines into 1-alkyl-2-(N-alkyl-N-ethylaminomethyl)aziridines using methyllithium

1-Alkyl-2-(bromomethyl)aziridines were transformed into 1-alkyl-2-(N-alkyl-N-ethylaminomethyl)aziridines upon treatment with 2-3 equiv. of methyllithium in THF or Et2O; the peculiarity in this transformation comprises the presence of an N-ethyl

2-Hydroxy-3-aminopropylsulfonamides

2-Hydroxy-3-aminopropylsulfonamides are provided along with methods for synthesizing and using such compounds, and chemical intermediates employed in the synthetic methods.

Sulfonamide-based compositions and methods

Methods are provided for using 2-hydroxy-3-aminopropylsulfonamides to mimic peptides and to modulate the chemical and/or biological activity of enzymes, particularly proteolytic enzymes. Also provided are compositions comprising the sulfonamides in admixt

Preparation and 3-Aza-Cope Rearrangement of N-Alkyl-N-allyl Enamines

The charge-accelerated rearrangement of N-allyl-N-isobutyl enamine substrates to γ,δ-unsaturated imine products and subsequent reduction to the corresponding N-alkyl δ,ε-unsaturated amines is reported.Several routes to the N-allyl-N-isobutyl enamine