943896-07-9

Basic information

• Product Name: (+)-hostmanin A
• Synonyms: (+)-hostmanin A
• CAS NO: 943896-07-9
• Molecular Weight: 408.538
• Mol File: 943896-07-9.mol

Chemical Properties

• CAS DataBase Reference: (+)-hostmanin A(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-hostmanin A(943896-07-9)
• EPA Substance Registry System: (+)-hostmanin A(943896-07-9)

Safety Data

• Hazardous Substances Data: 943896-07-9(Hazardous Substances Data)

Upstream product

• 4573-50-6 (-)-piperitone 
• 77129-49-8 1-(2,6-dihydroxy-4-methoxyphenyl)-3-phenyl-2-propen-1-one 
• 35241-55-5 1-(2,6-dihydroxy-4-methoxy-phenyl)-3-phenyl-propan-1-one 
• 491-04-3 piperitol 
• 1273019-47-8 1-{2-hydroxy-4-methoxy-6-methoxymethoxy-3-[(1R,6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl]phenyl}-3-phenylpropan-1-one 
• 1273019-46-7 (E)-1-{2-hydroxy-4-methoxy-6-methoxymethoxy-3-[(1R,6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl]phenyl}-3-phenylprop-2-en-1-one 
• 1273019-44-5 2'-hydroxy-4'-methoxy-6'-methoxymethoxy-3'-[(1R,6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl]acetophenone 
• 1013913-57-9 1-{2,6-dihydroxy-4-methoxy-3-[(1R,6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl]phenyl}ethanone 

Relevant articles and documents

Enantioselective Total Syntheses of (+)-Hostmanin A, (-)-Linderol A, (+)-Methyllinderatin and Structural Reassignment of Adunctin E

A one-step protocol has been developed for the enantioselective synthesis of hexahydrodibenzofuran derivatives using a modified Friedel-Crafts reaction. The developed method was applied to the synthesis of a series of natural products including (+)-hostmanin A, (+)-methyllinderatin, and (-)-linderol A. The synthetic and spectroscopic data investigations led to the structural reassignment of natural product adunctin E, which was further confirmed by single-crystal X-ray analysis. (Chemical Presented).

The first total syntheses of (+)-hostmanin a and (+)-methyllinderatin

The first total syntheses of (+)-hostmanin A (1) and (+)-methyllinderatin (3) were achieved in four steps from a known compound, 1-{2, 6-dihydroxy-4-methoxy-3-[(1R, 6R)-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-yl] phenyl}ethanone (6). The absolute config