943995-82-2Relevant articles and documents
Tetrahydroquinoline sulfonamides as vasopressin 1b receptor anatgonists
Scott, Jack D.,Miller, Michael W.,Li, Sarah W.,Lin, Sue-Ing,Vaccaro, Henry A.,Hong, Liwu,Mullins, Deborra E.,Guzzi, Mario,Weinstein, Jay,Hodgson, Robert A.,Varty, Geoffrey B.,Stamford, Andrew W.,Chan, Tin-Yau,McKittrick, Brian A.,Greenlee, William J.,Priestley, Tony,Parker, Eric M.
scheme or table, p. 6018 - 6022 (2010/06/16)
Vasopressin 1b (V1b) antagonists have been postulated as possible treatments for depression and anxiety. A novel series of potent and selective V1b antagonists has been identified starting from an in-house screen hit. The incorporation of a sulfonamide li
