944059-52-3Relevant academic research and scientific papers
Synthesis of the tricyclic core of colchicine via a dienyne tandem ring-closing metathesis reaction
Boyer, Francois-Didier,Hanna, Issam
, p. 2293 - 2295 (2008/02/05)
The synthesis of the tricyclic framework of colchicine has been achieved using a tandem ring-closing metathesis reaction of dienynes as the key step. In this process, both seven-membered rings B and C were formed in one step. Oxidation of tertiary allylic
