94413-70-4 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(2-methylpyridin-4-yl)methanamine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex molecular structures, contributing to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Development:
In the agrochemical industry, 1-(2-methylpyridin-4-yl)methanamine is utilized as a building block for the creation of novel agrochemicals, potentially enhancing crop protection and yield through its incorporation into pesticides and other agricultural products.
Used in Neurological Disorder Treatment:
1-(2-methylpyridin-4-yl)methanamine is studied for its potential use in treating neurological disorders, leveraging its chemical properties to target specific pathways or receptors in the nervous system, offering new avenues for therapeutic intervention.
Used in Antimicrobial and Antiviral Applications:
1-(2-methylpyridin-4-yl)methanamine has been investigated for its antimicrobial and antiviral properties, suggesting its use as an active ingredient in antimicrobial agents to combat resistant bacteria and viruses, contributing to the development of new treatments for infectious diseases.
Used in Materials Science:
1-(2-methylpyridin-4-yl)methanamine is researched for its potential role in the development of novel materials, where its unique chemical structure could be employed to create new polymers, coatings, or other materials with specific properties for various industrial applications.
Used in Organic Synthesis:
As a building block in organic synthesis, 1-(2-methylpyridin-4-yl)methanamine is used to construct a wide range of organic compounds, demonstrating its versatility and importance in the synthesis of complex organic molecules for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 94413-70-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,4,1 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 94413-70:
(7*9)+(6*4)+(5*4)+(4*1)+(3*3)+(2*7)+(1*0)=134
134 % 10 = 4
So 94413-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2/c1-6-4-7(5-8)2-3-9-6/h2-4H,5,8H2,1H3
94413-70-4Relevant academic research and scientific papers
Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology
Mejdrová, Ivana,Chalupská, Dominika,Pla?ková, Pavla,Müller, Christin,?ála, Michal,Klíma, Martin,Baumlová, Adriana,H?ebabecky, Hubert,Procházková, Eli?ka,Dejmek, Milan,Strunin, Dmytro,Weber, Jan,Lee, Gary,Matou?ová, Marika,Mertlíková-Kaiserová, Helena,Ziebuhr, John,Birkus, Gabriel,Boura, Evzen,Nencka, Radim
supporting information, p. 100 - 118 (2017/04/26)
Phosphatidylinositol 4-kinase IIIβ (PI4KB) is indispensable for the replication of various positive-sense single stranded RNA viruses, which hijack this cellular enzyme to remodel intracellular membranes of infected cells to set up the functional replication machinery. Therefore, the inhibition of this PI4K isoform leads to the arrest of viral replication. Here, we report on the synthesis of novel PI4KB inhibitors, which were rationally designed based on two distinct structural types of inhibitors that bind in the ATP binding side of PI4KB. These “hybrids” not only excel in outstanding inhibitory activity but also show high selectivity to PI4KB compared to other kinases. Thus, these compounds exert selective nanomolar or even subnanomolar activity against PI4KB as well as profound antiviral effect against hepatitis C virus, human rhinovirus, and coxsackievirus B3. Our crystallographic analysis unveiled the exact position of the side chains and explains their extensive contribution to the inhibitory activity.
NOVEL SULFONIMIDOYLPURINONE COMPOUNDS AND DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION
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Page/Page column 131, (2016/12/01)
The present invention relates to compounds of formula (I), wherein R 1, R2 and R3 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
TACHYKININ RECEPTOR ANTAGONISTS
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Page 28, (2010/02/10)
The present invention relates to selective NK-1 receptor antagonists of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of disorders associated with an excess of tachykinins.