94416-66-7

Basic information

• Product Name: 3,4-Dimethylbenzylbromide
• Synonyms: 4-(broMoMethyl)-1,2-diMethylbenzene
• CAS NO: 94416-66-7
• Molecular Formula: C₉H₁₁Br
• Molecular Weight: 199.09
• Mol File: 94416-66-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 237.4±9.0℃ (760 Torr)
• Flash Point: 103.2±11.8℃
• Appearance: /
• Density: 1.314±0.06 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: 3,4-Dimethylbenzylbromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dimethylbenzylbromide(94416-66-7)
• EPA Substance Registry System: 3,4-Dimethylbenzylbromide(94416-66-7)

Safety Data

• Hazardous Substances Data: 94416-66-7(Hazardous Substances Data)

Usage

General Description

3,4-Dimethylbenzylbromide is a chemical compound with the molecular formula C9H11Br. It is a brominated derivative of 3,4-dimethylbenzyl, and is widely used in organic synthesis and pharmaceutical research. 3,4-Dimethylbenzylbromide is a colorless to pale yellow liquid with a strong, pungent odor. It is highly reactive and can undergo various chemical reactions, including nucleophilic substitution and addition reactions. 3,4-Dimethylbenzylbromide is commonly used as a reagent in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. It is important to handle this compound with care, as it is toxic and can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 50-00-0 formaldehyd 
• 95-47-6 o-xylene 
• 5973-71-7 3,4-dimethylbenzaldehyde 
• 619-04-5 3,4-dimethylbenzoic acid 
• 6966-10-5 3,4-dimethylbenzyl alcohol 

Downstream Products

• 15255-93-3 N-(3.4-Dimethyl-benzyloxy)-carbamidsaeure-ethylester 
• 5553-51-5 N-(3,4-Dimethyl-benzyl)-N-(3,4-dimethyl-benzyloxy)-carbamidsaeure-ethylester 
• 617714-65-5 1-(3,4-dimethyl-benzyl)-piperidin-4-one 
• 401573-46-4 ethyl 2-amino-3-(3,4-dimethylphenyl)propanoate 
• 686298-35-1 4-(3,4-dimethyl-phenyl)-3,3-bis-ethoxycarbonyl-butanoic acid-tert-butylester 
• 1356199-62-6 7-[3-(benzylideneamino)methyl-4-(3',4'-dimethylbenzyloxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid 
• 1400793-16-9 C₂₄H₃₇N₃O₅ 
• 4136-92-9 2,2-dimethyl-3-(3,4-dimethylphenyl)propanal 
• 70090-73-2 1,2-Dimethyl-4-prop-2-ynyl-benzene 

Relevant articles and documents

OPSIN-BINDING LIGANDS, COMPOSITIONS AND METHODS OF USE

Compounds and compositions are disclosed that are useful for treating ophthalmic conditions caused by or related to production of toxic visual cycle products that accumulate in the eye, such as dry adult macular degeneration, as well as conditions caused by or related to the misfolding of mutant opsin proteins and/or the mis-localization of opsin proteins. Compositions of these compounds alone or in combination with other therapeutic agents are also described, along with therapeutic methods of using such compounds and/or compositions. Methods of synthesizing such agents are also disclosed.

Synthesis and in vitro antibacterial activity of gemifloxacin derivatives containing a substituted benzyloxime moiety

A series of novel gemifloxacin (GMFX) derivatives containing a substituted benzyloxime moiety with remarkable improvement in lipophilicity were synthesized. The target compounds evaluated for their in vitro antibacterial activity against representative strains. Our results reveal that most of the target compounds have considerable potency against all of the tested Gram-positive strains including MRSA and MRSE (MIC: 90: 1 μg/mL) is 8-fold more active than GMFX, and 2-fold more active than GMFX and moxifloxacin against MRSE clinical isolates (MIC90: 4 μg/mL). Crown Copyright

An improved method for the regiospecific synthesis of polysubstituted [2.2]paracyclophanes

4,16-Disubstituted, 4,7,12,15-tetrasubstituted, 4,8,12,16-tetrasubstituted and 4,5,7,8,12,13,15,16-octasubstituted [2.2]paracyclophanes can be prepared in significantly improved yields and excellent regiospecificities via the Winberg 1,6-elimination-dimerization reaction from substituted (4-methylbenzyl) trimethylammonium hydroxides. Using 2-chloro-phenothiazine instead of phenothiazine as a polymerization inhibitor results in a doubling of product yields. Georg Thieme Verlag Stuttgart.