944239-98-9Relevant academic research and scientific papers
An efficient bismuth(III) chloride-catalyzed synthesis of 1,1-di-arylalkenes via Friedel-Crafts reaction of acyl chloride or vinyl chloride with arenes
Sun, Hongbin,Hua, Ruimao,Chen, Songjie,Yin, Yingwu
, p. 1919 - 1925 (2006)
In the presence of catalytic amount of bismuth(III) chloride, the reactions of acyl chlorides or vinyl chlorides with arenes afforded 1,1-diarylalkenes in 25-82% isolated yield. In the case of the reaction of acyl chlorides with arenes, the procedure includes an initial Friedel-Crafts acylation, subsequent formation of vinyl chlorides and final Friedel-Crafts-type vinylation of another arene molecule with vinyl chloride. This paper reports the first Lewis acid-catalyzed cleavage of the C-Cl bond of vinyl chloride and its application in the synthesis of multiply subtituted alkenes.
