944262-94-6

Basic information

• Product Name: 2-(5-hydroxymethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione
• Synonyms: 2-(5-hydroxymethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione
• CAS NO: 944262-94-6
• Molecular Weight: 393.181
• Mol File: 944262-94-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(5-hydroxymethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-hydroxymethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione(944262-94-6)
• EPA Substance Registry System: 2-(5-hydroxymethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione(944262-94-6)

Safety Data

• Hazardous Substances Data: 944262-94-6(Hazardous Substances Data)

Upstream product

• 309712-97-8 5-(tert-butyl-dimethyl-silanyloxymethyl)-2-methyl-phenylamine 
• 85-44-9 phthalic anhydride 
• 389091-74-1 5-(tert-butyl-dimethyl-silanyloxymethyl)-4-iodo-2-methyl-phenylamine 
• 944263-04-1 2-[5-(tert-butyl-dimethyl-silanyloxymethyl)-4-iodo-2-methyl-phenyl]-isoindole-1,3-dione 
• 81863-45-8 3-(hydroxymethyl)-6-methylaniline 

Downstream Products

• 887142-49-6 2-[4-Iodo-2-methyl-5-((R)-2,2,6,6-tetramethyl-4-oxo-tetrahydro-pyran-3-ylmethyl)-phenyl]-isoindole-1,3-dione 
• 887142-50-9 trifluoro-methanesulfonic acid 3-[5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-iodo-4-methyl-benzyl]-2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl ester 
• 944262-95-7 2-(4-Iodo-5-{(S)-4-[(E)-(S)-2-methoxymethyl-pyrrolidin-1-ylimino]-2,2,6,6-tetramethyl-tetrahydro-pyran-3-ylmethyl}-2-methyl-phenyl)-isoindole-1,3-dione 
• 389091-80-9 2-{5-[(S)-Hydroxy-((R)-2,2,6,6-tetramethyl-4-oxo-tetrahydro-pyran-3-yl)-methyl]-4-iodo-2-methyl-phenyl}-isoindole-1,3-dione 
• 389091-87-6 2-{4-Iodo-2-methyl-5-[(S)-((R)-2,2,6,6-tetramethyl-4-oxo-tetrahydro-pyran-3-yl)-triethylsilanyloxy-methyl]-phenyl}-isoindole-1,3-dione 
• 944262-97-9 2-[5-((S)-Hydroxy-{(R)-4-[(E)-(S)-2-methoxymethyl-pyrrolidin-1-ylimino]-2,2,6,6-tetramethyl-tetrahydro-pyran-3-yl}-methyl)-4-iodo-2-methyl-phenyl]-isoindole-1,3-dione 
• 944263-05-2 2-[5-((R)-Hydroxy-{(R)-4-[(E)-(S)-2-methoxymethyl-pyrrolidin-1-ylimino]-2,2,6,6-tetramethyl-tetrahydro-pyran-3-yl}-methyl)-4-iodo-2-methyl-phenyl]-isoindole-1,3-dione 
• 389091-67-2 Trifluoro-methanesulfonic acid (R)-3-{(S)-[5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-iodo-4-methyl-phenyl]-triethylsilanyloxy-methyl}-2,2,6,6-tetramethyl-3,6-dihydro-2H-pyran-4-yl ester 
• 389091-71-8 5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-iodo-4-methyl-benzaldehyde 
• 887142-47-4 2-(5-bromomethyl-4-iodo-2-methyl-phenyl)-isoindole-1,3-dione 

Relevant articles and documents

Nodulisporic acid A synthetic studies. 1. Overall strategy and construction of a western hemisphere subtarget.

In this, the first of two Letters, we outline our overall strategy for the construction of (+)-nodulisporic acid A (1), a representative member of a new class of indole diterpenes. In addition, we describe the efficient assembly of (-)-6, an advanced western hemisphere subtarget, comprising the ABC rings of (+)-nodulisporic acid A (1). The synthesis proceeded in 9% overall yield (longest linear sequence, 11 steps), exploiting a Shibasaki-Mori tandem transmetalation-cyclization to construct ring B. [reaction: see text]