944315-82-6

Basic information

• Product Name: (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol
• Synonyms: (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol
• CAS NO: 944315-82-6
• Molecular Weight: 228.407
• Mol File: 944315-82-6.mol

Chemical Properties

• CAS DataBase Reference: (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol(944315-82-6)
• EPA Substance Registry System: (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol(944315-82-6)

Safety Data

• Hazardous Substances Data: 944315-82-6(Hazardous Substances Data)

Upstream product

• 1165952-91-9 cyclohexa-1,3-diene 
• 28981-66-0 (+/-)-3,4-dideoxyconduritol D 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 170211-25-3 (1R,2S)-1,2-dihydroxycyclohexa-3-ene 

Downstream Products

• 1313496-65-9 (R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enone 
• 309243-64-9 (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one 

Relevant articles and documents

Regiodivergent reactions through catalytic enantioselective silylation of chiral diols. Synthesis of sapinofuranone A

Through the use of an amino acid based imidazole catalyst, a regiodivergent silylation of chiral diols in cases where there is not a significant steric and electronic difference between the regioisotopic hydroxyl groups has been developed. This transformation allows for the conversion of racemic diols into regioisomeric, enantiomerically enriched, monosilylated products. The utility of this process is highlighted in the efficient enantioselective preparation of a useful synthetic intermediate and the natural product, sapinofuranone A.