309243-64-9

Basic information

• Product Name: (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one
• Synonyms: (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one
• CAS NO: 309243-64-9
• Molecular Weight: 240.418
• Mol File: 309243-64-9.mol

Chemical Properties

• CAS DataBase Reference: (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one(309243-64-9)
• EPA Substance Registry System: (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one(309243-64-9)

Safety Data

• Hazardous Substances Data: 309243-64-9(Hazardous Substances Data)

Upstream product

• 184653-97-2 (R)-4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 75-16-1 methylmagnesium bromide 
• 164577-42-8 <(4R)-(+)-tert-Butoxydimethylsiloxy>-2-cyclohexen-1-on 
• 57356-79-3 4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 309243-63-8 4-acetoxy-3-methyl-2-cyclohexen-1-one 
• 1313496-65-9 (R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enone 
• 944315-82-6 (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol 
• 170211-25-3 (1R,2S)-1,2-dihydroxycyclohexa-3-ene 
• 28981-66-0 (+/-)-3,4-dideoxyconduritol D 
• 1165952-91-9 cyclohexa-1,3-diene 

Downstream Products

• 1071838-14-6 C₁₃H₂₃BrO₂Si 
• 1199941-04-2 C₁₅H₂₆O₃Si 
• 1268840-57-8 C₁₇H₃₂O₂Si 
• 1268840-58-9 C₁₉H₃₆O₂Si 
• 1268840-68-1 C₁₉H₃₆O₂Si 
• 171231-07-5 (1S,5R)-cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanemethanol 
• 309243-65-0 methyl (1S,3R)-3-[(tert-butyldimethylsilyl)oxy]-2,2-dimethyl-6-oxo-cyclohexanecarboxylate 

Relevant articles and documents

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A straightforward enantioselective synthesis of both enantiomers of karahana lactone is described starting from enantiopure (R) or (S)-4-hydroxy-3-methyl-cyclohex-2-en-1-one. The key step of the sequence is an acid-induced domino reaction with three pathways running. Because of the first description of karahana lactone as a solid, the structure was secured by X-ray structural analysis. (C) 2000 Elsevier Science Ltd.