309243-64-9

Upstream product

• 184653-97-2 (R)-4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 164577-42-8 <(4R)-(+)-tert-Butoxydimethylsiloxy>-2-cyclohexen-1-on 
• 1313496-65-9 (R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enone 
• 944315-82-6 (1S,6R)-6-(tert-butyldimethylsilyloxy)cyclohex-2-enol 
• 170211-25-3 (1R,2S)-1,2-dihydroxycyclohexa-3-ene 
• 28981-66-0 (+/-)-3,4-dideoxyconduritol D 
• 1165952-91-9 cyclohexa-1,3-diene 
• 309243-63-8 4-acetoxy-3-methyl-2-cyclohexen-1-one 
• 57356-79-3 4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1071838-14-6 C₁₃H₂₃BrO₂Si 
• 1199941-04-2 C₁₅H₂₆O₃Si 
• 1268840-57-8 C₁₇H₃₂O₂Si 
• 1268840-58-9 C₁₉H₃₆O₂Si 
• 1268840-68-1 C₁₉H₃₆O₂Si 
• 171231-07-5 (1S,5R)-cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanemethanol 
• 309243-65-0 methyl (1S,3R)-3-[(tert-butyldimethylsilyl)oxy]-2,2-dimethyl-6-oxo-cyclohexanecarboxylate 

Relevant academic research and scientific papers

Total synthesis of kinamycins C, F, and J

The kinamycins are a series of naturally occurring compounds endowed with intriguing molecular architectures and potent biological properties, including antibiotic and antitumor activities. These novel diazofluorene-containing compounds defied chemical sy

A ring-closing metathesis approach to the bicyclo[4.3.1]decane core of caryolanes

A synthesis of highly substituted and sterically congested bicyclo[4.3.1]decenes, a structure embedded in the core 4,7,6-tricyclic system of natural caryolanes, was successfully achieved via a ring-closing metathesis (RCM) reaction of syn-1,3-diene substi

Regiodivergent reactions through catalytic enantioselective silylation of chiral diols. Synthesis of sapinofuranone A

Through the use of an amino acid based imidazole catalyst, a regiodivergent silylation of chiral diols in cases where there is not a significant steric and electronic difference between the regioisotopic hydroxyl groups has been developed. This transformation allows for the conversion of racemic diols into regioisomeric, enantiomerically enriched, monosilylated products. The utility of this process is highlighted in the efficient enantioselective preparation of a useful synthetic intermediate and the natural product, sapinofuranone A.

Asymmetric [4+2] cycloadditions employing 1,3-dienes derived from (R)-4-t-butyldimethyl-silyloxy-2-cyclohexen-1-one

1,3-Dienes derived from (R)-4-t-butyldimethylsilyloxy-2-cyclohexen-1-one react with activated dienophiles to form predominately (or sometimes exclusively) syn/endo products. These controlled [4+2] cycloadditions increase the asymmetric complexity from one

Straightforward enantioselective synthesis of both enantiomers of karahana lactone using a domino ring-closure sequence

A straightforward enantioselective synthesis of both enantiomers of karahana lactone is described starting from enantiopure (R) or (S)-4-hydroxy-3-methyl-cyclohex-2-en-1-one. The key step of the sequence is an acid-induced domino reaction with three pathways running. Because of the first description of karahana lactone as a solid, the structure was secured by X-ray structural analysis. (C) 2000 Elsevier Science Ltd.