94447-18-4 Usage
Derivative of pyrazole
yes
Contains functional groups
carboxylic acid, hydrazide
Has a methyl group attached to the pyrazole ring
yes
Has a phenyl group attached to the pyrazole ring
yes
Commonly used in organic synthesis and drug research
yes
Diverse applications in the pharmaceutical industry
yes
Studied for potential biological activities
antiviral, anticancer
Important chemical for medicinal chemistry research
yes
Check Digit Verification of cas no
The CAS Registry Mumber 94447-18-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,4,4 and 7 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 94447-18:
(7*9)+(6*4)+(5*4)+(4*4)+(3*7)+(2*1)+(1*8)=154
154 % 10 = 4
So 94447-18-4 is a valid CAS Registry Number.
94447-18-4Relevant articles and documents
Pyrazolecarboxylic acid hydrazides as antiinflammatory agents. New selective lipoxygenase inhibitors
Tihanyi,Feher,Gal,et al.
, p. 433 - 439 (2007/10/02)
The synthesis and antiinflammatory activity of some new pyrazolecarboxylic acid hydrazides 3, 4 and 5 substituted with alkyl, alkylidene, aryl and acyl groups are described. 3 were prepared by reaction of pyrazolecarboxylic acids, esters, acid chlorides or diketopiperazines with hydrazines. Upon reaction with carbonyl compounds 3 gave hydrazones 4. Acylation of 3 yielded mono or bisacyl compounds 5. The most potent antiinflammatory compounds were among the N'-aryl hydrazides. These showed high lipoxygenase inhibitory activity but hardly inhibited cyclooxygenase enzyme.