944904-93-2 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-Fluorophenyl)pyrimidine-5-carbaldehyde is used as a key intermediate in the development of potential drug candidates. Its unique structure allows for the creation of new molecules with therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
FPCA serves as a building block in the synthesis of agrochemicals, helping to develop new compounds with pesticidal or herbicidal properties. Its incorporation into these products can lead to more effective and targeted agricultural solutions.
Used in Material Science:
2-(4-Fluorophenyl)pyrimidine-5-carbaldehyde may have applications in material science, where its unique chemical properties can be utilized to create novel materials with specific characteristics, such as improved stability or reactivity.
Used in Organic Synthesis:
FPCA is a valuable compound in organic synthesis, where it can be used to construct complex organic molecules with diverse applications. Its versatility allows chemists to explore new synthetic pathways and develop innovative compounds for various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 944904-93-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,0 and 4 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 944904-93:
(8*9)+(7*4)+(6*4)+(5*9)+(4*0)+(3*4)+(2*9)+(1*3)=202
202 % 10 = 2
So 944904-93-2 is a valid CAS Registry Number.
944904-93-2Relevant academic research and scientific papers
Synthesis of Soai Type 2-Arylpyrimidine-5-carbaldehydes through Desulfurative Cross-Coupling with Arylboronic Acids
Maltsev, Oleg V.,Rausch, Rodger,Quan, Zheng-Jun,Hintermann, Lukas
, p. 7426 - 7432 (2016/02/20)
A two-step synthesis of 2-arylpyrimidine-5-carbaldehydes, which are of relevance as substrates for Soai's asymmetric autocatalysis, was realized by exploiting a hidden threefold symmetry in the target core structure. Condensation of Arnold's C 3-symmetric vinamidinium cation with S-methylisothiouronium sulfate provides 2-methylsulfanyl-pyrimidine-5-carbaldehyde; introduction of aryl groups at C-2 of the latter was accomplished by a Liebeskind-Srogl palladium-catalyzed desulfurative (de-methylsulfanylative) coupling with aryl boronic acids to obtain the target compounds 1 (14 examples, 60-95 % yield). 2-Arylpyrimidine-5-carbaldehydes, which are of relevance as substrates in Soai's asymmetric autocatalysis, are prepared through Liebeskind-Srogl coupling of aryl boronic acids with 2-methylthiopyrimidine-5-carbaldehyde; the latter is obtained in a hydrolytic condensation of two symmetric amidinium salts.
Heteroarylacrylamides and their use as pharmaceuticals for the stimulation of the expression of endothelial NO synthase
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Page/Page column 62, (2008/12/06)
The present invention relates to heteroarylacrylamides of the formula I, in which Het, X, Ra, Rb, R1, R2 and R3 have the meanings indicated in the claims, which modulate the transcription of endotheli
