94494-29-8

Upstream product

• 37091-40-0 2,4-Dimethyl-N-(4-methyl-phenyl)-buta-1,3-dien-1,4-sultam 
• 4885-02-3 Dichloromethyl methyl ether 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 204379-65-7 1-[ω-(4-Acetamido-phenylsulfonylamino)-butyl]-2,4-dimethyl-pyridinium-5-(N-4-tolyl)-sulfonamidat 
• 204379-60-2 N-(4-Aminobutyl)-2,4-dimethyl-pyridinium-5-(N-4-tolyl)-sulfonamidat 
• 184433-66-7 4,6-Dimethyl-1-oxy-pyridine-3-sulfonic acid p-tolylamide 

Relevant academic research and scientific papers

4-(1-methyl-2-sulfamoylvinyl)pyrazoles by ring transformation of 1,1-dioxo-2H-1,2-thiazine-4-carbaldehydes with hydrazines

As masked 1,3-dicarbonyl compounds, 1,1-dioxo-2H-1,2-thiazine-4-carbaldehydes (2a-e, 7) undergo ring transformations with nucleophilic hydrazines to produce 4-[1-methyl-2-(arylsulfamoyl)vinyl]pyrazoles (9a-i). For 9h, an X-ray structural analysis is reported. With less nucleophilic semicarbazide and p-nitrophenylhydrazine the hydrazones (11a,b) were isolated. The carbaldehydes 2a-e, 7 and 8a,b were synthesized by formylation of the 1,1-dioxo-2H-1,2-thiazines 1a-e, 5 and 6a,b with dichloromethyl methyl ether/ TiCl4. In the case of 1a-e mixtures of 4- and 6-carbaldehydes (2a-e/3a-e) were obtained, which, however, could be used for the synthesis of pyrazoles. Johann Ambrosius Barth 1997.