94494-31-2

Basic information

• Product Name: 2H-1,2-Thiazine-6-carboxaldehyde, 2-(4-chlorophenyl)-3,5-dimethyl-, 1,1-dioxide
• CAS NO: 94494-31-2
• Molecular Formula: C13H12ClNO3S
• Molecular Weight: 297.762
• Mol File: 94494-31-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-1,2-Thiazine-6-carboxaldehyde, 2-(4-chlorophenyl)-3,5-dimethyl-, 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2-Thiazine-6-carboxaldehyde, 2-(4-chlorophenyl)-3,5-dimethyl-, 1,1-dioxide(94494-31-2)
• EPA Substance Registry System: 2H-1,2-Thiazine-6-carboxaldehyde, 2-(4-chlorophenyl)-3,5-dimethyl-, 1,1-dioxide(94494-31-2)

Safety Data

• Hazardous Substances Data: 94494-31-2(Hazardous Substances Data)

Upstream product

• 63673-40-5 2,4-Dimethyl-N-(4-chlor-phenyl)-buta-1,3-dien-1,4-sultam 
• 68-12-2 N,N-dimethyl-formamide 
• 4885-02-3 Dichloromethyl methyl ether 

Relevant articles and documents

4-(1-methyl-2-sulfamoylvinyl)pyrazoles by ring transformation of 1,1-dioxo-2H-1,2-thiazine-4-carbaldehydes with hydrazines

As masked 1,3-dicarbonyl compounds, 1,1-dioxo-2H-1,2-thiazine-4-carbaldehydes (2a-e, 7) undergo ring transformations with nucleophilic hydrazines to produce 4-[1-methyl-2-(arylsulfamoyl)vinyl]pyrazoles (9a-i). For 9h, an X-ray structural analysis is reported. With less nucleophilic semicarbazide and p-nitrophenylhydrazine the hydrazones (11a,b) were isolated. The carbaldehydes 2a-e, 7 and 8a,b were synthesized by formylation of the 1,1-dioxo-2H-1,2-thiazines 1a-e, 5 and 6a,b with dichloromethyl methyl ether/ TiCl4. In the case of 1a-e mixtures of 4- and 6-carbaldehydes (2a-e/3a-e) were obtained, which, however, could be used for the synthesis of pyrazoles. Johann Ambrosius Barth 1997.