944940-75-4

Basic information

• Product Name: ethyl 2-(3-phenylpropylene)acetoaceacetate
• Synonyms: ethyl 2-(3-phenylpropylene)acetoaceacetate
• CAS NO: 944940-75-4
• Molecular Weight: 244.29
• Mol File: 944940-75-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl 2-(3-phenylpropylene)acetoaceacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(3-phenylpropylene)acetoaceacetate(944940-75-4)
• EPA Substance Registry System: ethyl 2-(3-phenylpropylene)acetoaceacetate(944940-75-4)

Safety Data

• Hazardous Substances Data: 944940-75-4(Hazardous Substances Data)

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 185259-16-9 MRS 1097 

Relevant articles and documents

Rearrangement of propargylic esters: Metal-based stereospecific synthesis of (E)- and (Z)-knoevenagel derivatives

Alkoxy-substituted propargylic esters undergo regioselective 1,3-acyloxy migration in the presence of Pt(II) and Cu(I) catalysts, allowing the preparation of α-ylidene-β-keto and -malonate esters. The reaction proved to also be stereodivergent as the Pt(II) and the Cu(I) catalysts perform the isomerization with complementary Z/E selectivity. Moreover, alkynyl-conjugated Knoevenagel products are produced from (bisalkynyl)methyl acetates. In such a case, the reaction is chemoselective as the 1,3-acetyl migration takes place through the alkoxyalkyne group in preference over the phenylalkyne group. The resulting (E)-alkynylenone unit suffers metal-catalyzed cyclization into the furyl ring, generating a copper(I) carbene species. Copyright