Cas 944949-26-2,(4aR)-10bR-(4-chlorophenylsulfonyl)-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyrano[3,4-b]pyridine-3(S)-acetonitrile

944949-26-2

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Basic information

Product Name: (4aR)-10bR-(4-chlorophenylsulfonyl)-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyrano[3,4-b]pyridine-3(S)-acetonitrile
Synonyms: (4aR)-10bR-(4-chlorophenylsulfonyl)-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyrano[3,4-b]pyridine-3(S)-acetonitrile
CAS NO:944949-26-2
Molecular Formula:
Molecular Weight: 438.882
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (4aR)-10bR-(4-chlorophenylsulfonyl)-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyrano[3,4-b]pyridine-3(S)-acetonitrile(CAS DataBase Reference)
NIST Chemistry Reference: (4aR)-10bR-(4-chlorophenylsulfonyl)-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyrano[3,4-b]pyridine-3(S)-acetonitrile(944949-26-2)
EPA Substance Registry System: (4aR)-10bR-(4-chlorophenylsulfonyl)-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyrano[3,4-b]pyridine-3(S)-acetonitrile(944949-26-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 944949-26-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 944949-26-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,4,9,4 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 944949-26:
(8*9)+(7*4)+(6*4)+(5*9)+(4*4)+(3*9)+(2*2)+(1*6)=222
222 % 10 = 2
So 944949-26-2 is a valid CAS Registry Number.

944949-26-2Upstream product

944953-05-3 3-[4-(4-chloro-benzenesulfonyl)-5,8-difluoro-chroman-3-yl-(R)-amino]-5-hydroxy-pentanenitrile

944949-26-2Downstream Products

944949-23-9 (4aR)-10bR-[(4-chlorophenyl)sulfonyl]-7,10-difluoro-1,3,4,4a,5,10b-hexahydro-2H-[1]benzopyran[3,4-b]pyridine-3(S)-ethylamine

944949-26-2Relevant academic research and scientific papers

BENZENESULFONYL-CHROMANE, THIOCHROMANE, TETRAHYDRONAPHTHALENE AND RELATED GAMMA SECRETASE INHIBITORS

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Page/Page column 459; 482, (2009/03/07)

Disclosed are novel gamma secretase inhibitors of the formula (I): or a pharmaceutically acceptable salt, solvate, or ester thereof, wherein L1, n, X, Ar, Y, Z, Q, and Q1 are as defined herein. Also disclosed are methods for inhibiti

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