944952-82-3

Upstream product

• 944952-84-5 (3R,4R,5S)-4-(4-hydroxyphenyl)-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxypiperidin-3-ol 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 944952-80-1 6-[(3R,4R,5S)-4-(4-methoxyphenyl)-1-(toluene-4-sulfonyl)-5-triisopropylsilanyloxypiperidin-3-yloxymethyl]-4-(3-methoxypropyl)-4H-benzo[1,4]oxazin-3-one 

Relevant academic research and scientific papers

Substituted piperidines as therapeutic compounds

Described are compounds of the general formula (I) and pharmaceutically acceptable salt thereof, in which R2, R3, W,and X have the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II an

SUBSTITUTED 4-PHENYLPIPERIDINES

The application relates to substituted 4-phenylpiperidines of the general formula and their salts, preferably their pharmaceutically acceptable salts, in which R2, R3, W and X have the meanings explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors.