945-61-9Relevant academic research and scientific papers
An Unusually Fast Chapman-like Thermal Rearrangement in the Solid State
Dessolin, Michele,Golfier, Michel
, p. 38 - 39 (1986)
Some 5-methoxy-2-aryl-1,3,4-oxadiazoles undergo a 1,3 O-to-N thermal rearrangement of the methyl group, which takes place unusually easily, and much faster in the solid state than in the melt.
I2 mediated synthesis of 5-substituted-3-methyl/benzyl-1,3,4-oxadiazol-2(3H)-ones via sequential condensation/oxidative cyclization and rearrangement
Patel, Shyam Sunder,Chandna, Nisha,Kumar, Shreemoyee,Jain, Nidhi
, p. 5683 - 5689 (2016/07/06)
A simple and efficient iodine-assisted protocol for the synthesis of 5-substituted-3-methyl/benzyl-1,3,4-oxadiazol-2(3H)-ones has been developed. The reaction involves a sequential condensation followed by tandem oxidative cyclization and rearrangement of
