945006-75-7

Upstream product

• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 945006-76-8 1-(4-methoxybenzyl)-2-methylsulfanyl-5-vinylimidazole-4-carboxylic acid 
• 945006-78-0 4-chloro-1-(4-methoxy-benzyl)-2-methylsulfanyl-1H-imidazo[4,5-c]pyridine 
• 945006-81-5 4-bromo-1-(4-methoxy-benzyl)-2-methylsulfanyl-1H-imidazo[4,5-c]pyridine 
• 945006-77-9 1-(4-methoxybenzyl)-2-methylsulfanyl-4-(N-methoxyimino-1-chloromethyl)-5-vinylimidazole 
• 945006-80-4 1-(4-methoxybenzyl)-2-methylsulfanyl-4-(N-methoxyimino-1-bromomethyl)-5-vinylimidazole 
• 945006-79-1 2-[1-(4-methoxybenzyl)-1H-imidazo[4,5-c]pyridin-4-yl]pyrrole-1-carboxylic acid tert-butyl ester 
• 945006-64-4 1-(4-methoxybenzyl)-4-(1H-pyrrol-2-yl)-1H-imidazo[4,5-c]pyridine 

Relevant academic research and scientific papers

Total synthesis of ageladine A, an angiogenesis inhibitor from the marine sponge Agelas nakamurai

A 12-step total synthesis of the tricyclic heteroaromatic marine metabolite ageladine A has been achieved using a 6π-azaelectrocyclization and a Suzuki-Miyaura coupling of N-Boc-pyrrole-2-boronic acid with a chloropyridine as key steps.

Application of a 6π-1-azatriene electrocyclization strategy to the total synthesis of the marine sponge metabolite ageladine A and biological evaluation of synthetic analogues

(Chemical Equation Presented) A 12-step synthesis of the angiogenesis inhibitory marine metabolite ageladine A is reported. The key steps include a 6π-1-azatriene electrocyclization for formation of the pyridine ring and a Suzuki-Miyaura coupling of N-Boc